The new trailer for Netflix’s Manic has been released. Lead by Emma Stone and Jonah Hill reuniting for the first time since SuperbadManiac tells the stories of Annie Landsberg and Owen Milgrim, two strangers drawn to the late stages of a mysterious pharmaceutical trial. Things do not go as planned. The Netflix limited series is from creator, Cary Joji Fukunaga.

The trailer seems to have the characters traveling through a multiverse finding themselves in different eras and relationships. This looks to be the makings of an Emmy darling with a stellar cast and a high concept series that should fit well into the sci-fi TV landscape, which has only been getting stronger in recent seasons.

Maniac arrives September 21 only on Netflix.

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